ARTERIAL HEALING AND STENT FAILURE AFTER CORONARY STENTING

Abstract

This article examines the clinical factors associated with arterial healing and
stent failure following coronary stenting, as well as high-risk patient groups.
Successful coronary stenting depends on effective arterial healing, which may be
impaired by factors such as patient comorbidities, lesion characteristics, and
procedural technique. Stent failure, manifested as ISR or ST, remains a significant
challenge. This article summarizes current evidence on the impact of factors such
as diabetes mellitus, chronic kidney disease, inflammation, and genetic
predisposition on arterial healing and stent outcomes. It also analyzes the influence
of lesion complexity, stent type (drug-eluting vs. bare-metal), and antiplatelet
therapy regimens on the risk of ISR and ST. Finally, this review identifies highrisk
patient groups, including those with complex coronary artery disease, prior
stent failures, and poor medication adherence, and discusses strategies for
managing them to improve long-term outcomes after coronary stenting.