Assessment of endothelial dysfunction in patients with ankylosing spondyloarthritis due to previous coronavirus infection

Abstract

The priority of vascular damage in the pathogenesis of ankylosing spondyloarthritis
(AS) is one of the current issues. Damage to the vascular endothelium in the early stages of
ankylosing spondyloarthritis, changes in the hemostasis system with the subsequent development
of atherosclerotic processes in the vessels correlate with the severity of the disease. We studied the
severity of endothelial dysfunction by determining endothelin- 1 in serum and determining the
vasoregulatory function of the endothelium by Doppler ultrasound diagnostics of the brachial
artery