Despite a comprehensive study of the problem of infertility and miscarriage,
insufficiently studied prognostic, therapeutic and preventive aspects of pregnancy
preservation and their complexity, as well as socio-economic factors make this topic
very relevant, requires a more in-depth study of the clinical, diagnostic, hormonal
aspects of this problem. To increase the effectiveness of assisted reproductive
technologies in women with a history of miscarriage. Materials and methods of
research. This study included 117 women of reproductive age with a history of
miscarriage. The materials for the study were blood samples of patients. The results
of the study. In women with a threat of miscarriage, the indicators were higher by
1.21 (p<0.05) and 1.37 (p<0.05) in the two groups, respectively. Conclusion.
Microcirculatory changes that have appeared in the placenta lead to the appearance
of inflammatory foci, which in turn disrupt the secretory function, and it disrupts the
normal synthesis of hormones leading to miscarriage
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